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Stress can weaken our cardiovascular system in two ways--by increasing heart rate and by increasing blood pressure. In more extreme cases and especially for people with cardiovascular disease, increased beating can cause damage to the heart. Many people experience a small change in blood pressure during stressful times. When this happens to a greater extreme, it can be very dangerous. Often, people who have extreme changes in blood pressure due to stress have other physical problems that aggravate their blood pressure as well.