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Benign essential blepharospasm (BEB) is a progressive neurological disorder characterized by involuntary muscle contractions and spasms of the eyelid muscles. It is not life-threatening It is a form of dystonia, a movement disorder in which sustained muscle contractions cause twitching and repetitive movements.
BEB begins gradually with occasional eye blinking and/or irritation. Other symptoms may include involuntary winking or squinting of one or both eyes, increasing difficulty in keeping the eyes open, and light sensitivity. Generally, the spasms occur during the day, disappear in sleep, and reappear after waking. As the condition progresses, the spasms may intensify, forcing the eyelids to remain closed for long periods of time, and thereby causing substantial visual disturbance or functional blindness. It is important to note that the blindness is caused solely by the uncontrollable closing of the eyelids and not by a dysfunction of the eyes.
Blepharospasm should not be confused with: Ptosis - drooping of the eyelids caused by weakness or paralysis of a levator muscle of the upper eyelid, Blepharitis - an inflammatory condition of the lids due to infection or allergies or Hemifacial spasm - a non-dystonic condition involving various muscles on one side of the face, often including the eyelid, and caused by irritation of the facial nerve.
BEB occurs in both men and women, although it is especially common in middle-aged and elderly women.
In most cases of BEB the treatment of choice is botulinum toxin injections, which relax the muscles and stop the spasms. Other treatment options include medications (drug therapy) or surgery.
Stress makes all movement disorders, including blepharospasm, worse. Some patients may benefit from a course of stress management from an occupational therapist. Support from family and friends is also important.
With botulinum toxin treatment most individuals with BEB have substantial relief of symptoms. Although some may experience side effects such as drooping eyelids, blurred or double vision, and eye dryness, these side effects are usually only temporary
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